| Date | Opponent | Time |
| 09/03/11 | at Texas | L, 34-9 |
| 09/10/11 | vs. Purdue | W, 24-22 |
| 09/24/11 | at Baylor | L, 56-31 |
| 10/01/11 | at Southern Miss | L, 48-24 |
| 10/08/11 | vs. Memphis | W, 28-6 |
| 10/15/11 | at Marshall | L, 24-20 |
| 10/22/11 | vs. Tulsa | L, 38-20 |
| 10/27/11 | at Houston | L, 73-34 |
| 11/05/11 | vs. UTEP | W, 41-37 |
| 11/12/11 | at Northwestern | L, 28-6 |
| 11/19/11 | vs. Tulane | W, 19-7 |
| 11/26/11 | at SMU | L, 27-24 |
Rice Owls
SMU Mustangs